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Pharmacology - 02.06.2023
Health - Pharmacology - 02.06.2023
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Health - Pharmacology - 01.06.2023
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Health - Pharmacology - 01.06.2023
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Pharmacology
Results 1 - 20 of 2090.
Neutrons show how pre-filled syringes clog
The hypodermic needles on pre-filled syringes can clog when stored incorrectly. A research team subjected the process to a detailed and systematic investigation, including activities at the Research Neutron Source Heinz Maier-Leibnitz (FRM II) of the Technical University of Munich (TUM). The results will help improve manufacturing and storage conditions accordingly.
The hypodermic needles on pre-filled syringes can clog when stored incorrectly. A research team subjected the process to a detailed and systematic investigation, including activities at the Research Neutron Source Heinz Maier-Leibnitz (FRM II) of the Technical University of Munich (TUM). The results will help improve manufacturing and storage conditions accordingly.
Multi-cancer blood test shows real promise in NHS trial
An NHS trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms, in England or Wales. The test also also correctly identified the original site of cancer in 85% of those cases.
An NHS trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms, in England or Wales. The test also also correctly identified the original site of cancer in 85% of those cases.
Prisoner healthcare puts patients at risk
The healthcare needs of prisoners in England are not being met and essential changes are needed to ensure patient safety, according to new research led by Cardiff University. The first nationwide analysis of patient safety in prisons in England found that prisoners are experiencing delayed access to healthcare services and medication-related harm.
The healthcare needs of prisoners in England are not being met and essential changes are needed to ensure patient safety, according to new research led by Cardiff University. The first nationwide analysis of patient safety in prisons in England found that prisoners are experiencing delayed access to healthcare services and medication-related harm.
Antipsychotic drug use increased in Canadian long-term care homes in first year of pandemic
Other aspects of treatment in long-term care homes generally remained the same a year into the pandemic While most aspects of care quality in long-term care homes did not differ in the first year of the pandemic from pre-pandemic levels, a new study shows that the use of antipsychotic drugs increased in all provinces.
Other aspects of treatment in long-term care homes generally remained the same a year into the pandemic While most aspects of care quality in long-term care homes did not differ in the first year of the pandemic from pre-pandemic levels, a new study shows that the use of antipsychotic drugs increased in all provinces.
New Class of Antibiotics to Fight Resistant Bacteria
Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Rapid test for sepsis
In the case of blood poisoning, the bacteria in the blood must be identified as fast as possible so that a life-saving therapy can be started. researchers have now developed "sepsis sensors" with magnetic nanoparticles that detect bacterial pathogens within a short period of time and identify suitable candidates for antibiotic therapies.
In the case of blood poisoning, the bacteria in the blood must be identified as fast as possible so that a life-saving therapy can be started. researchers have now developed "sepsis sensors" with magnetic nanoparticles that detect bacterial pathogens within a short period of time and identify suitable candidates for antibiotic therapies.
Native tobacco plants reborn as ’biofactories’ for medicines
University of Queensland researchers have shown Australian tobacco plants could be used as 'biofactories' to manufacture medicines on a large scale. Professor David Craik Dr Mark Jackson from UQ's Institute for Molecular Bioscience have demonstrated native wild tobacco, Nicotiana benthamiana, can potentially produce large quantities of drugs, cheaper and more sustainably than industrial manufacturing methods.
University of Queensland researchers have shown Australian tobacco plants could be used as 'biofactories' to manufacture medicines on a large scale. Professor David Craik Dr Mark Jackson from UQ's Institute for Molecular Bioscience have demonstrated native wild tobacco, Nicotiana benthamiana, can potentially produce large quantities of drugs, cheaper and more sustainably than industrial manufacturing methods.
Nanoparticles deliver brain cancer treatment
University of Queensland researchers have developed a nanoparticle to take a chemotherapy drug into fast growing, aggressive brain tumours. Research team lead Dr Taskeen Janjua from UQ's School of Pharmacy said the new silica nanoparticle can be loaded with temozolomide, a small molecule drug used to treat tumours known as glioblastoma.
University of Queensland researchers have developed a nanoparticle to take a chemotherapy drug into fast growing, aggressive brain tumours. Research team lead Dr Taskeen Janjua from UQ's School of Pharmacy said the new silica nanoparticle can be loaded with temozolomide, a small molecule drug used to treat tumours known as glioblastoma.
KU Leuven and the Institut Pasteur of Dakar join forces for local vaccine production in Africa
Currently, only a meagre 1% of the vaccines needed for Africa are produced locally. The ambition is to raise this number to 60% by 2040. Together, KU Leuven and the Institut Pasteur of Dakar are working to overcome several significant challenges, including the need for continuous cooling, time-consuming methods for certain blood analyses in clinical studies, and the lack of vaccines against several deadly tropical diseases.
Currently, only a meagre 1% of the vaccines needed for Africa are produced locally. The ambition is to raise this number to 60% by 2040. Together, KU Leuven and the Institut Pasteur of Dakar are working to overcome several significant challenges, including the need for continuous cooling, time-consuming methods for certain blood analyses in clinical studies, and the lack of vaccines against several deadly tropical diseases.
Biomarkers for the Progression of Type 2 Diabetes Identified
Researcher Guy Rutter and his colleagues in Europe, Canada and the United States have discovered molecules in samples taken from 3,000 diabetic patients that could help personalize treatments. Guy Rutter, researcher at the Centre de recherche du CHUM (CRCHUM), Imperial College London and professor in the Department of Medicine at the Université de Montréal Credit: CRCHUM This research was carried out as part of the European RHAPSODY project (Risk Assessment and Progression of Diabetes).
Researcher Guy Rutter and his colleagues in Europe, Canada and the United States have discovered molecules in samples taken from 3,000 diabetic patients that could help personalize treatments. Guy Rutter, researcher at the Centre de recherche du CHUM (CRCHUM), Imperial College London and professor in the Department of Medicine at the Université de Montréal Credit: CRCHUM This research was carried out as part of the European RHAPSODY project (Risk Assessment and Progression of Diabetes).
Wirelessly-powered ’smart bandage’ could provide drug-free wound care
A new generation of wirelessly-powered, environmentally-friendly 'smart bandages' could help patients with non-healing wounds avoid infections, scientists say. The bandage could help improve the quality of life of people who live with chronic non-healing wounds, which currently frequently require painful cleaning and treatment.
A new generation of wirelessly-powered, environmentally-friendly 'smart bandages' could help patients with non-healing wounds avoid infections, scientists say. The bandage could help improve the quality of life of people who live with chronic non-healing wounds, which currently frequently require painful cleaning and treatment.
Schizophrenia drug as new therapy against dementia
A clinical trial will investigate the drug's efficacy in dementia patients. A common feature of many neurodegenerative diseases are pathological protein deposits in the brain. These protein aggregates cause nerve cells to die and, as a result, entire brain areas to shrink, which manifests itself in affected individuals as progressive dementia.
A clinical trial will investigate the drug's efficacy in dementia patients. A common feature of many neurodegenerative diseases are pathological protein deposits in the brain. These protein aggregates cause nerve cells to die and, as a result, entire brain areas to shrink, which manifests itself in affected individuals as progressive dementia.
A metabolic process in cancer cells could unlock a possible treatment for glioblastoma
UCLA-led study could lead to new strategy for treating aggressive brain cancer Health + Behavior UCLA-led study could lead to new strategy for treating aggressive brain cancer A UCLA-led team identified a genetic alteration that occurs in 60% of people who are diagnosed with glioblastoma; that mutation disrupts the cancer cells' metabolism.
UCLA-led study could lead to new strategy for treating aggressive brain cancer Health + Behavior UCLA-led study could lead to new strategy for treating aggressive brain cancer A UCLA-led team identified a genetic alteration that occurs in 60% of people who are diagnosed with glioblastoma; that mutation disrupts the cancer cells' metabolism.
Five types of heart failure identified using AI tools
Five subtypes of heart failure that could potentially be used to predict future risk for individual patients have been identified in a new study led by UCL researchers. Heart failure is an umbrella term for when the heart is unable to pump blood around the body properly. Current ways of classifying heart failure do not accurately predict how the disease is likely to progress.
Five subtypes of heart failure that could potentially be used to predict future risk for individual patients have been identified in a new study led by UCL researchers. Heart failure is an umbrella term for when the heart is unable to pump blood around the body properly. Current ways of classifying heart failure do not accurately predict how the disease is likely to progress.
Drug that could combat drug-resistant infections
The machine-learning algorithm identified a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings. Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.
The machine-learning algorithm identified a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings. Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.
Anticoagulation treatment after an ischemic stroke should be started earlier
An international clinical trial, which involved experts from Glasgow, has concluded that anticoagulation treatment could be safely started earlier than current recommended guidelines in patients following ischemic stroke with atrial fibrillation. The study - published in the New England Journal of Medicine and led by the led by the Stroke Center, Inselspital, University Hospital Bern, and the University of Bern - found the chances of suffering a recurrent event with earlier treatment were likely to be lower compared to a later start, without an increase in risk of complications.
An international clinical trial, which involved experts from Glasgow, has concluded that anticoagulation treatment could be safely started earlier than current recommended guidelines in patients following ischemic stroke with atrial fibrillation. The study - published in the New England Journal of Medicine and led by the led by the Stroke Center, Inselspital, University Hospital Bern, and the University of Bern - found the chances of suffering a recurrent event with earlier treatment were likely to be lower compared to a later start, without an increase in risk of complications.
A marine worm, life saver
In 2020, in the midst of the COVID-19 crisis, we spoke with Franck Zal, a doctor in marine biology from Sorbonne University and founder of the company Hemarina. At the time, HEMO2life - their flagship product created from the hemoglobin of the marine worm, the arenicole - was envisaged to improve the oxygenation of patients suffering from acute respiratory distress syndrome.
In 2020, in the midst of the COVID-19 crisis, we spoke with Franck Zal, a doctor in marine biology from Sorbonne University and founder of the company Hemarina. At the time, HEMO2life - their flagship product created from the hemoglobin of the marine worm, the arenicole - was envisaged to improve the oxygenation of patients suffering from acute respiratory distress syndrome.
Covid-19 vaccination reduces mortality also in critically ill corona patients
A study from the University of Vienna shows a positive effect of vaccination even in patients requiring oxygen. Previous studies have shown that the mortality rate of Corona patients hospitalized and requiring oxygen therapy is similar no matter if they are vaccinated or unvaccinated.
A study from the University of Vienna shows a positive effect of vaccination even in patients requiring oxygen. Previous studies have shown that the mortality rate of Corona patients hospitalized and requiring oxygen therapy is similar no matter if they are vaccinated or unvaccinated.
New measurement equipment at the University: Studying receptor proteins using EPR spectroscopy
News from Studying proteins with novel methods is Dr Matthias Elgeti's speciality. An EPR spectrometer is helping him to study the structure and dynamics of G protein-coupled receptors (GPCRs). His work is concerned with the side effects of drugs and the regulation of bodily functions such as hunger.
News from Studying proteins with novel methods is Dr Matthias Elgeti's speciality. An EPR spectrometer is helping him to study the structure and dynamics of G protein-coupled receptors (GPCRs). His work is concerned with the side effects of drugs and the regulation of bodily functions such as hunger.
New vaccine concept against SARS-CoV-2 successfully tested
Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19. This vaccine is based on a modified coronavirus that can enter body cells and trigger an effective immune response but cannot multiply in the body. In animal studies, the vaccine effectively protected against the disease and even prevented virus transmission.
Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19. This vaccine is based on a modified coronavirus that can enter body cells and trigger an effective immune response but cannot multiply in the body. In animal studies, the vaccine effectively protected against the disease and even prevented virus transmission.
Campus WATERLOO - Jun 2
Outstanding student researchers recognized with Governor General's Gold Medal
Outstanding student researchers recognized with Governor General's Gold Medal
Environment - Jun 2
Berkeley Talks transcript: Climate grief: Embracing loss as a catalyst for regeneration
Berkeley Talks transcript: Climate grief: Embracing loss as a catalyst for regeneration